| 1. Jornada | 15.05.2021 | Montevideo Wanderers | - | Boston River | 1:0 | ||||
| 2. Jornada | 23.05.2021 | Montevideo Wanderers | - | Deportivo Maldonado | 0:0 | ||||
| 4. Jornada | 07.06.2021 | Montevideo Wanderers | - | Peñarol | 0:0 | ||||
| 5. Jornada | 11.06.2021 | Montevideo City Torque | - | Montevideo Wanderers | 2:1 | ||||
| 10. Jornada | 10.07.2021 | Montevideo Wanderers | - | River Plate | 1:2 | ||||
| 11. Jornada | 17.07.2021 | Cerro Largo | - | Montevideo Wanderers | 2:0 | ||||
| 12. Jornada | 31.07.2021 | Montevideo Wanderers | - | Progreso | 2:0 |  |
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| 13. Jornada | 09.08.2021 | Sud América | - | Montevideo Wanderers | 1:0 | ||||
| 14. Jornada | 16.08.2021 | Montevideo Wanderers | - | Plaza Colonia | 0:2 | ||||
| 15. Jornada | 20.08.2021 | Fénix | - | Montevideo Wanderers | 2:1 | |
Uruguay