| 1. Jornada | 06.08.2021 | FC Den Bosch | - | Helmond Sport | 2:0 | ||||
| 2. Jornada | 13.08.2021 | Helmond Sport | - | AZ Alkmaar (J) | 1:2 | ||||
| 3. Jornada | 20.08.2021 | MVV | - | Helmond Sport | 3:2 | ||||
| 9. Jornada | 01.10.2021 | Helmond Sport | - | Jong Ajax | 3:1 | ||||
| 11. Jornada | 15.10.2021 | Helmond Sport | - | ADO Den Haag | 0:0 | ||||
| 12. Jornada | 22.10.2021 | Telstar | - | Helmond Sport | 2:2 | ||||
| 18. Jornada | 03.12.2021 | Helmond Sport | - | FC Volendam | 1:1 |
Países Bajos