| 1. Jornada | 17.02.2019 | Cerro Largo | - | Danubio | 2:0 | ||||
| 2. Jornada | 23.02.2019 | Plaza Colonia | - | Danubio | 0:1 | ||||
| 3. Jornada | 03.03.2019 | Danubio | - | CA Cerro | 1:0 | ||||
| 4. Jornada | 10.03.2019 | River Plate | - | Danubio | 1:1 | ||||
| 5. Jornada | 16.03.2019 | Danubio | - | Nacional | 2:0 | ||||
| 7. Jornada | 31.03.2019 | Danubio | - | Progreso | 3:2 |  |
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| 9. Jornada | 13.04.2019 | Danubio | - | Defensor Sporting | 1:1 | ||||
| 10. Jornada | 20.04.2019 | Rampla Juniors | - | Danubio | 0:0 |  |
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| 11. Jornada | 05.05.2019 | Danubio | - | Juventud de Las Piedras | 4:3 | ||||
| 12. Jornada | 11.05.2019 | Liverpool | - | Danubio | 0:5 | ||||
| 13. Jornada | 18.05.2019 | Danubio | - | Montevideo Wanderers | 0:2 | ||||
| 14. Jornada | 26.05.2019 | Racing | - | Danubio | 0:2 | ||||
| 15. Jornada | 02.06.2019 | Danubio | - | Boston River | 1:0 |
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