| 1. Jornada | 08.08.2021 | US Mondorf | - | CS FOLA Esch | 2:0 |  |
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| 2. Jornada | 15.08.2021 | CS FOLA Esch | - | Etzella Ettelbruck | 2:0 | ||||
| 5. Jornada | 11.09.2021 | CS FOLA Esch | - | Progrès Niedercorn | 2:0 | |
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| 6. Jornada | 19.09.2021 | UNA Strassen | - | CS FOLA Esch | 2:2 | ||||
| 9. Jornada | 17.10.2021 | CS FOLA Esch | - | RM Hamm Benfica | 2:1 | ||||
| 12. Jornada | 21.11.2021 | Jeunesse Esch | - | CS FOLA Esch | 3:3 | ||||
| 15. Jornada | 11.12.2021 | CS FOLA Esch | - | Union Titus Pétange | 3:0 | |
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| 17. Jornada | 13.02.2022 | CS FOLA Esch | - | FC Differdange 03 | 2:4 | ||||
| 26. Jornada | 24.04.2022 | CS FOLA Esch | - | Jeunesse Esch | 1:0 |
Cabo Verde