| 1. Jornada | 18.09.2021 | Club Necaxa [] | - | Santos Laguna [] | 4:0 |  |
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| 3. Jornada | 02.10.2021 | Club Necaxa [] | - | Deportivo Guadalajara [] | 0:2 | ||||
| 4. Jornada | 09.10.2021 | UANL Tigres [] | - | Club Necaxa [] | 3:1 | ||||
| 5. Jornada | 16.10.2021 | Atlas Guadalajara [] | - | Club Necaxa [] | 1:2 |  |
México