| 3. Jornada | 21.08.2021 | Livingston FC | - | Motherwell FC | 1:2 |  |
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| 4. Jornada | 28.08.2021 | Motherwell FC | - | Dundee FC | 1:0 | ||||
| 5. Jornada | 11.09.2021 | Motherwell FC | - | Aberdeen FC | 2:0 | |
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| 6. Jornada | 19.09.2021 | Rangers FC | - | Motherwell FC | 1:1 | ||||
| 7. Jornada | 25.09.2021 | Motherwell FC | - | Ross County FC | 2:1 | ||||
| 8. Jornada | 02.10.2021 | Heart of Midlothian | - | Motherwell FC | 2:0 | |
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| 9. Jornada | 16.10.2021 | Motherwell FC | - | Celtic FC | 0:2 | ||||
| 10. Jornada | 23.10.2021 | Dundee United | - | Motherwell FC | 2:1 | |
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| 11. Jornada | 27.10.2021 | Motherwell FC | - | St. Mirren FC | 2:2 | ||||
| 14. Jornada | 20.11.2021 | Motherwell FC | - | Heart of Midlothian | 2:0 | ||||
| 15. Jornada | 27.11.2021 | Dundee FC | - | Motherwell FC | 3:0 | ||||
| 16. Jornada | 30.11.2021 | Motherwell FC | - | Dundee United | 1:0 | ||||
| 20. Jornada | 26.12.2021 | Motherwell FC | - | Livingston FC | 2:1 | ||||
| 25. Jornada | 06.02.2022 | Motherwell FC | - | Celtic FC | 0:4 |
Inglaterra