| 19. Jornada | 19.01.2001 | Club Brugge KV | - | Excelsior Mouscron | 2:2 |  |
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| 20. Jornada | 28.01.2001 | Excelsior Mouscron | - | KV Mechelen | 4:2 | ||||
| 21. Jornada | 04.02.2001 | K.S.C. Eendracht Aalst | - | Excelsior Mouscron | 1:0 | ||||
| 22. Jornada | 10.02.2001 | Excelsior Mouscron | - | Sint-Truidense VV | 1:0 |  |
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| 23. Jornada | 16.02.2001 | KVC Westerlo | - | Excelsior Mouscron | 1:0 |  |
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| 25. Jornada | 10.03.2001 | RSC Charleroi | - | Excelsior Mouscron | 1:3 | ||||
| 27. Jornada | 30.03.2001 | RSC Anderlecht | - | Excelsior Mouscron | 3:3 | ||||
| 28. Jornada | 07.04.2001 | Excelsior Mouscron | - | Lierse SK (old) | 1:2 | ||||
| 29. Jornada | 14.04.2001 | KRC Genk | - | Excelsior Mouscron | 4:0 | ||||
| 33. Jornada | 12.05.2001 | Excelsior Mouscron | - | Standard Liège | 1:1 |
Bélgica