| 1. Jornada | 19.09.2021 | SS San Giovanni | - | AC Juvenes/Dogana | 4:0 | ||||
| 2. Jornada | 25.09.2021 | AC Juvenes/Dogana | - | SP Tre Penne | 0:1 | ||||
| 3. Jornada | 03.10.2021 | SS Folgore/Falciano | - | AC Juvenes/Dogana | 2:1 |  |
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| 4. Jornada | 16.10.2021 | SS Pennarossa | - | AC Juvenes/Dogana | 0:0 | |
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| 6. Jornada | 23.10.2021 | AC Juvenes/Dogana | - | FC Fiorentino | 0:1 | ||||
| 7. Jornada | 31.10.2021 | SP La Fiorita | - | AC Juvenes/Dogana | 2:2 | ||||
| 12. Jornada | 11.12.2021 | AC Juvenes/Dogana | - | AC Libertas | 1:7 | ||||
| 13. Jornada | 18.12.2021 | SS Cosmos | - | AC Juvenes/Dogana | 1:1 |
Italia
San Marino