| 4. Jornada | 04.02.2021 | Montevideo City Torque | - | Defensor Sporting | 0:0 |  |
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| 5. Jornada | 07.02.2021 | Defensor Sporting | - | Plaza Colonia | 3:2 | ||||
| 6. Jornada | 11.02.2021 | Progreso | - | Defensor Sporting | 3:3 | ||||
| 7. Jornada | 15.02.2021 | Defensor Sporting | - | Fénix | 2:2 | ||||
| 8. Jornada | 18.02.2021 | CA Cerro | - | Defensor Sporting | 0:0 | ||||
| 11. Jornada | 08.03.2021 | Nacional | - | Defensor Sporting | 2:1 |
Uruguay
Italia