| 1. Jornada | 14.01.2021 | LD Alajuelense | - | Municipal Pérez Zeledón | 2:0 | ||||
| 2. Jornada | 17.01.2021 | Santos de Guápiles | - | Municipal Pérez Zeledón | 2:0 |  |
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| 3. Jornada | 22.01.2021 | Municipal Pérez Zeledón | - | CS Cartaginés | 2:1 | |
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| 4. Jornada | 24.01.2021 | Municipal Grecia | - | Municipal Pérez Zeledón | 0:0 | ||||
| 5. Jornada | 01.02.2021 | Municipal Pérez Zeledón | - | Jicaral | 1:2 | ||||
| 7. Jornada | 08.02.2021 | Limón FC | - | Municipal Pérez Zeledón | 1:1 | |
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| 6. Jornada | 12.02.2021 | Municipal Pérez Zeledón | - | Deportivo Saprissa | 1:1 | ||||
| 8. Jornada | 16.02.2021 | Municipal Pérez Zeledón | - | Guadalupe | 1:3 | ||||
| 9. Jornada | 21.02.2021 | Municipal Pérez Zeledón | - | AD San Carlos | 1:1 | ||||
| 17. Jornada | 11.04.2021 | Deportivo Saprissa | - | Municipal Pérez Zeledón | 1:1 | ||||
| 15. Jornada | 15.04.2021 | Municipal Pérez Zeledón | - | Municipal Grecia | 1:1 | |
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| 19. Jornada | 22.04.2021 | Guadalupe | - | Municipal Pérez Zeledón | 0:1 | ||||
| 20. Jornada | 27.04.2021 | AD San Carlos | - | Municipal Pérez Zeledón | 0:1 | ||||
| 21. Jornada | 02.05.2021 | Municipal Pérez Zeledón | - | CS Herediano | 0:3 | ||||
| 22. Jornada | 13.05.2021 | Municipal Pérez Zeledón | - | Sporting FC | 3:1 |
Costa Rica