| 12. Jornada | 02.10.2021 | Platense Zacatecoluca | - | AD Chalatenango | 2:1 | ||||
| 16. Jornada | 31.10.2021 | Luis Ángel Firpo | - | AD Chalatenango | 4:2 | ||||
| 19. Jornada | 14.11.2021 | AD Chalatenango | - | Jocoro FC | 2:0 |  |
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| 20. Jornada | 17.11.2021 | FAS | - | AD Chalatenango | 1:1 | ||||
| 21. Jornada | 21.11.2021 | Municipal Limeño | - | AD Chalatenango | 0:3 |
El Salvador