| 4. Jornada | 12.08.2018 | CF América | - | CF Monterrey | 3:0 | ||||
| 5. Jornada | 19.08.2018 | CF Monterrey | - | Pumas UNAM | 1:0 | ||||
| 6. Jornada | 23.08.2018 | Lobos BUAP | - | CF Monterrey | 1:2 | ||||
| 7. Jornada | 26.08.2018 | CF Monterrey | - | Monarcas Morelia | 2:2 |  |
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| 8. Jornada | 01.09.2018 | Puebla FC | - | CF Monterrey | 2:1 | |
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| 9. Jornada | 16.09.2018 | CF Monterrey | - | Deportivo Guadalajara | 2:4 | ||||
| 10. Jornada | 24.09.2018 | UANL Tigres | - | CF Monterrey | 0:0 | ||||
| 11. Jornada | 30.09.2018 | CF Monterrey | - | Club Tijuana | 3:0 |  |
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| 12. Jornada | 07.10.2018 | Cruz Azul | - | CF Monterrey | 2:1 | ||||
| 13. Jornada | 21.10.2018 | CF Monterrey | - | Deportivo Toluca | 2:1 | ||||
| 14. Jornada | 27.10.2018 | Santos Laguna | - | CF Monterrey | 1:0 | ||||
| 15. Jornada | 04.11.2018 | CF Monterrey | - | CD Veracruz | 2:0 | ||||
| 16. Jornada | 11.11.2018 | Club Necaxa | - | CF Monterrey | 1:1 | ||||
| 17. Jornada | 25.11.2018 | CF Monterrey | - | Atlas Guadalajara | 3:1 | |
México