| 1. Jornada | 18.07.2021 | Sport Boys | - | Cienciano | 1:4 | ||||
| 2. Jornada | 24.07.2021 | Ayacucho FC | - | Sport Boys | 1:2 |  |
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| 3. Jornada | 01.08.2021 | Sport Boys | - | Alianza Lima | 0:0 | |
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| 4. Jornada | 05.08.2021 | Alianza Universidad | - | Sport Boys | 2:0 | ||||
| 5. Jornada | 08.08.2021 | Academia Cantolao | - | Sport Boys | 0:2 | ||||
| 6. Jornada | 15.08.2021 | Sport Boys | - | Universidad San Martín | 2:0 | ||||
| 8. Jornada | 22.08.2021 | Sport Boys | - | Universitario de Deportes | 0:0 | ||||
| 9. Jornada | 29.08.2021 | Sport Huancayo | - | Sport Boys | 1:1 | |
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| 7. Jornada | 03.09.2021 | Deportivo Municipal | - | Sport Boys | 0:1 | ||||
| 10. Jornada | 13.09.2021 | Sport Boys | - | César Vallejo | 2:2 | ||||
| 11. Jornada | 18.09.2021 | Deportivo Binacional | - | Sport Boys | 1:2 | ||||
| 12. Jornada | 22.09.2021 | Sport Boys | - | Cusco FC | 3:2 | |
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| 14. Jornada | 01.10.2021 | Sport Boys | - | Alianza Atlético | 3:1 | ||||
| 15. Jornada | 16.10.2021 | Universidad Técnica | - | Sport Boys | 1:1 | ||||
| 16. Jornada | 22.10.2021 | Sport Boys | - | Mannucci | 3:3 | |
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| 17. Jornada | 30.10.2021 | Sporting Cristal | - | Sport Boys | 1:1 |
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