| 1. Jornada | 01.08.2021 | Xelaju MC | - | Cobán Imperial | 3:0 | ||||
| 2. Jornada | 07.08.2021 | Cobán Imperial | - | Sololá FC | 0:0 | ||||
| 4. Jornada | 14.08.2021 | Cobán Imperial | - | Achuapa | 2:0 | ||||
| 3. Jornada | 18.08.2021 | Nueva Concepción | - | Cobán Imperial | 2:1 |  |
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| 7. Jornada | 29.08.2021 | Cobán Imperial | - | Antigua GFC | 0:2 | ||||
| 9. Jornada | 11.09.2021 | Cobán Imperial | - | Santa Lucía | 0:1 |
Guatemala