| 4. Jornada | 29.01.2025 | FC Juárez [Sub 23] | - | Santos Laguna [Sub 23] | 0:0 |  |
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| 5. Jornada | 02.02.2025 | Santos Laguna [Sub 23] | - | Puebla FC [Sub 23] | 0:0 | |
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| 6. Jornada | 07.02.2025 | Club Necaxa [Sub 23] | - | Santos Laguna [Sub 23] | 0:1 | ||||
| 7. Jornada | 14.02.2025 | Mazatlán FC [Sub 23] | - | Santos Laguna [Sub 23] | 1:5 | ||||
| 9. Jornada | 19.02.2025 | Santos Laguna [Sub 23] | - | Cruz Azul [Sub 23] | 0:2 | ||||
| 13. Jornada | 30.03.2025 | Santos Laguna [Sub 23] | - | Atlético San Luis [Sub 23] | 1:0 | ||||
| 14. Jornada | 06.04.2025 | Deportivo Toluca [Sub 23] | - | Santos Laguna [Sub 23] | 1:0 |
México