| 8. Jornada | 01.03.2022 | Deportivo Toluca [Sub 20] | - | Club Tijuana [Sub 20] | 3:1 | ||||
| 11. Jornada | 18.03.2022 | Club Tijuana [Sub 20] | - | FC Juárez [Sub 20] | 1:1 | ||||
| 12. Jornada | 03.04.2022 | UANL Tigres [Sub 20] | - | Club Tijuana [Sub 20] | 1:2 | ||||
| 14. Jornada | 16.04.2022 | Club Tijuana [Sub 20] | - | CF América [Sub 20] | 4:0 | ||||
| 15. Jornada | 19.04.2022 | Deportivo Guadalajara [Sub 20] | - | Club Tijuana [Sub 20] | 1:1 | ||||
| 17. Jornada | 30.04.2022 | CF Monterrey [Sub 20] | - | Club Tijuana [Sub 20] | 3:0 |
México