| 2. Jornada | 31.10.2021 | Pharco FC | - | Pyramids FC | 1:2 |  |
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| 3. Jornada | 04.11.2021 | Pyramids FC | - | Ittihad El Iskandary | 3:0 | |
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| 4. Jornada | 19.11.2021 | Al Masry Club | - | Pyramids FC | 2:2 | ||||
| 5. Jornada | 22.11.2021 | Pyramids FC | - | El Sharkia Lel Dokhan | 3:0 | ||||
| 7. Jornada | 21.12.2021 | Pyramids FC | - | Tala'ea El Gaish SC | 3:0 | |
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| 6. Jornada | 25.12.2021 | ENPPI | - | Pyramids FC | 1:1 | |
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| 12. Jornada | 04.03.2022 | Al Mokawloon | - | Pyramids FC | 0:2 | ||||
| 8. Jornada | 08.03.2022 | Al Ahly SC | - | Pyramids FC | 3:0 | ||||
| 11. Jornada | 06.04.2022 | Pyramids FC | - | Zamalek | 2:3 | ||||
| 13. Jornada | 09.04.2022 | Pyramids FC | - | Ghazl Al Mehalla | 1:0 | ||||
| 16. Jornada | 27.04.2022 | Pyramids FC | - | Ceramica Cleopatra | 0:1 | ||||
| 17. Jornada | 01.05.2022 | El Gouna | - | Pyramids FC | 1:2 | |
Palestina