| 1. Jornada | 16.10.2021 | Espérance Zarzis | - | Olympique Béja | 0:2 | ||||
| 2. Jornada | 23.10.2021 | CS Chebba | - | Espérance Zarzis | 0:0 | ||||
| 3. Jornada | 30.10.2021 | Espérance Zarzis | - | AS Rejiche | 0:0 | ||||
| 4. Jornada | 04.11.2021 | Étoile du Sahel | - | Espérance Zarzis | 1:1 | ||||
| 5. Jornada | 07.11.2021 | Espérance Zarzis | - | AS Soliman | 0:0 | ||||
| 7. Jornada | 21.11.2021 | Espérance Zarzis | - | US Monastir | 0:1 |  |
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