| 1. Jornada | 24.07.2021 | KV Oostende | - | Sporting Charleroi | 0:3 | ||||
| 3. Jornada | 08.08.2021 | Oud-Heverlee Leuven | - | Sporting Charleroi | 1:1 | ||||
| 4. Jornada | 13.08.2021 | Sporting Charleroi | - | Royal Antwerp FC | 1:1 | ||||
| 6. Jornada | 28.08.2021 | Sporting Charleroi | - | K Beerschot VA | 5:2 | ||||
| 7. Jornada | 12.09.2021 | Gante | - | Sporting Charleroi | 2:3 |  |
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| 8. Jornada | 18.09.2021 | Sporting Charleroi | - | Club Brugge KV | 0:1 | ||||
| 9. Jornada | 26.09.2021 | Sporting Charleroi | - | KV Mechelen | 0:2 | ||||
| 10. Jornada | 02.10.2021 | KV Kortrijk | - | Sporting Charleroi | 2:2 | ||||
| 11. Jornada | 17.10.2021 | Sporting Charleroi | - | KRC Genk | 2:0 | ||||
| 18. Jornada | 10.12.2021 | Sporting Charleroi | - | KV Oostende | 1:0 | ||||
| 21. Jornada | 27.12.2021 | Sporting Charleroi | - | Oud-Heverlee Leuven | 0:3 |
Senegal