| 1. Jornada | 06.02.2022 | FBC Melgar | - | Mannucci | 1:0 | ||||
| 3. Jornada | 20.02.2022 | Alianza Lima | - | Mannucci | 3:1 | ||||
| 4. Jornada | 26.02.2022 | Mannucci | - | Sport Huancayo | 0:1 | ||||
| 5. Jornada | 06.03.2022 | Academia Cantolao | - | Mannucci | 3:2 | ||||
| 6. Jornada | 12.03.2022 | Mannucci | - | Carlos Stein | 1:0 | ||||
| 7. Jornada | 22.03.2022 | Universidad San Martín | - | Mannucci | 1:3 | ||||
| 8. Jornada | 04.04.2022 | Mannucci | - | César Vallejo | 0:0 | ||||
| 9. Jornada | 09.04.2022 | Deportivo Municipal | - | Mannucci | 1:0 | ||||
| 10. Jornada | 16.04.2022 | Mannucci | - | Cienciano | 0:2 | ||||
| 11. Jornada | 24.04.2022 | Deportivo Binacional | - | Mannucci | 2:1 | ||||
| 12. Jornada | 01.05.2022 | Mannucci | - | AD Tarma | 1:1 | ||||
| 13. Jornada | 08.05.2022 | Ayacucho FC | - | Mannucci | 2:2 | ||||
| 14. Jornada | 15.05.2022 | Mannucci | - | Universitario de Deportes | 0:0 | ||||
| 15. Jornada | 22.05.2022 | Sport Boys | - | Mannucci | 1:4 | ||||
| 16. Jornada | 29.05.2022 | Mannucci | - | Atlético Grau | 1:0 | ||||
| 17. Jornada | 19.06.2022 | Alianza Atlético | - | Mannucci | 0:0 | ||||
| 18. Jornada | 24.06.2022 | Universidad Técnica | - | Mannucci | 1:2 | ||||
| 19. Jornada | 03.07.2022 | Mannucci | - | Sporting Cristal | 1:3 |
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