| 5. Jornada | 26.04.2021 | Independiente Petrolero | - | Jorge Wilstermann | 5:4 | ||||
| 6. Jornada | 01.05.2021 | Club Aurora | - | Independiente Petrolero | 3:0 | ||||
| 7. Jornada | 09.05.2021 | Independiente Petrolero | - | Atlético Palmaflor | 2:0 | ||||
| 10. Jornada | 22.07.2021 | Club San José | - | Independiente Petrolero | 1:3 | ||||
| 11. Jornada | 25.07.2021 | Independiente Petrolero | - | Royal Pari | 1:0 | ||||
| 13. Jornada | 04.08.2021 | Independiente Petrolero | - | Real Potosí | 2:1 | ||||
| 14. Jornada | 08.08.2021 | Nacional Potosí | - | Independiente Petrolero | 1:2 | ||||
| 15. Jornada | 13.08.2021 | Independiente Petrolero | - | CD Guabirá | 2:1 | ||||
| 17. Jornada | 22.08.2021 | Independiente Petrolero | - | Blooming | 3:0 | ||||
| 21. Jornada | 27.09.2021 | Independiente Petrolero | - | Club Aurora | 3:0 | ||||
| 25. Jornada | 01.11.2021 | Independiente Petrolero | - | Club San José | 4:0 |  |
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| 26. Jornada | 21.11.2021 | Royal Pari | - | Independiente Petrolero | 3:1 |
Brasil
Bolivia