| 1. Jornada | 05.08.2007 | UANL Tigres | - | Club San Luis | 0:0 | ||||
| 2. Jornada | 12.08.2007 | Club San Luis | - | Club Necaxa | 3:2 | ||||
| 3. Jornada | 19.08.2007 | Club San Luis | - | Cruz Azul | 3:1 | ||||
| 4. Jornada | 26.08.2007 | Deportivo Toluca | - | Club San Luis | 2:1 |  |
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| 6. Jornada | 02.09.2007 | CF Pachuca | - | Club San Luis | 4:1 | ||||
| 7. Jornada | 09.09.2007 | Club San Luis | - | Deportivo Guadalajara | 0:0 | |
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| 8. Jornada | 16.09.2007 | Atlante | - | Club San Luis | 4:3 | |
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| 9. Jornada | 23.09.2007 | Club San Luis | - | CF América | 2:1 | |
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| 10. Jornada | 30.09.2007 | CF Monterrey | - | Club San Luis | 2:3 | ||||
| 11. Jornada | 07.10.2007 | Club San Luis | - | Puebla FC | 0:3 | ||||
| 12. Jornada | 14.10.2007 | Jaguares Chiapas | - | Club San Luis | 2:2 | ||||
| 13. Jornada | 21.10.2007 | Club San Luis | - | Pumas UNAM | 3:2 |  |
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| 14. Jornada | 27.10.2007 | UAG Tecos | - | Club San Luis | 2:3 | |
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| 15. Jornada | 01.11.2007 | Club San Luis | - | Monarcas Morelia | 2:1 | ||||
| 16. Jornada | 04.11.2007 | Atlas Guadalajara | - | Club San Luis | 1:1 | |
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| 17. Jornada | 11.11.2007 | Club San Luis | - | Santos Laguna | 2:2 |
Uruguay