| 1. Jornada | 27.07.2008 | Club San Luis | - | Monarcas Morelia | 2:2 | ||||
| 2. Jornada | 03.08.2008 | CF Pachuca | - | Club San Luis | 2:3 | ||||
| 6. Jornada | 07.08.2008 | Club San Luis | - | Cruz Azul | 2:1 | ||||
| 4. Jornada | 17.08.2008 | Atlas Guadalajara | - | Club San Luis | 0:1 | ||||
| 5. Jornada | 24.08.2008 | Club San Luis | - | UANL Tigres | 1:0 | ||||
| 7. Jornada | 31.08.2008 | Atlante | - | Club San Luis | 1:0 | ||||
| 8. Jornada | 14.09.2008 | Club San Luis | - | CF América | 1:2 | ||||
| 9. Jornada | 21.09.2008 | Pumas UNAM | - | Club San Luis | 0:1 | ||||
| 10. Jornada | 28.09.2008 | Club San Luis | - | Puebla FC | 1:1 | ||||
| 11. Jornada | 05.10.2008 | Indios Juárez | - | Club San Luis | 2:3 |  |
Uruguay