| 4. Jornada | 28.08.2021 | AS Saint-Priest | - | Lyon (CFA) | 1:3 | ||||
| 5. Jornada | 04.09.2021 | Lyon (CFA) | - | Étoile FC | 3:0 |  |
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| 6. Jornada | 11.09.2021 | GOAL FC | - | Lyon (CFA) | 2:0 | ||||
| 7. Jornada | 18.09.2021 | Lyon (CFA) | - | Aubagne FC | 3:1 |  |
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| 8. Jornada | 25.09.2021 | Jura Sud | - | Lyon (CFA) | 1:1 | ||||
| 9. Jornada | 09.10.2021 | Lyon (CFA) | - | Marsella (CFA) | 2:2 | ||||
| 10. Jornada | 23.10.2021 | Marignane Gignac FC | - | Lyon (CFA) | 4:0 | ||||
| 11. Jornada | 06.11.2021 | Lyon (CFA) | - | SC Toulon | 0:0 | ||||
| 12. Jornada | 20.11.2021 | Lyon (CFA) | - | RC Grasse | 1:0 | |
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| 14. Jornada | 11.12.2021 | Lyon (CFA) | - | Hyères FC | 3:2 | |
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| 13. Jornada | 18.12.2021 | Louhans-Cuiseaux | - | Lyon (CFA) | 1:2 | |
Brasil
