| 3. Jornada | 29.07.2018 | Real Potosí | - | Nacional Potosí | 2:3 |  |
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| 4. Jornada | 02.08.2018 | Blooming | - | Real Potosí | 5:0 | ||||
| 7. Jornada | 18.08.2018 | Real Potosí | - | CD Guabirá | 2:0 |  |
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| 8. Jornada | 25.08.2018 | Destroyers | - | Real Potosí | 2:1 | ||||
| 9. Jornada | 02.09.2018 | Real Potosí | - | Club San José | 0:5 | ||||
| 11. Jornada | 21.09.2018 | Real Potosí | - | Oriente Petrolero | 1:0 | |
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| 13. Jornada | 30.09.2018 | Club Aurora | - | Real Potosí | 3:2 | ||||
| 14. Jornada | 07.10.2018 | Universitario de Sucre | - | Real Potosí | 0:0 | ||||
| 16. Jornada | 25.10.2018 | Real Potosí | - | Sport Boys Warnes | 3:1 | ||||
| 17. Jornada | 30.10.2018 | Real Potosí | - | Blooming | 1:1 | ||||
| 18. Jornada | 03.11.2018 | The Strongest | - | Real Potosí | 5:1 | |
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| 19. Jornada | 11.11.2018 | Real Potosí | - | Jorge Wilstermann | 0:2 | ||||
| 22. Jornada | 18.11.2018 | Club San José | - | Real Potosí | 2:1 | ||||
| 26. Jornada | 19.12.2018 | Real Potosí | - | Club Aurora | 1:0 |
Bolivia