| 1. Jornada | 01.08.2021 | Real Estelí FC | - | H&H Export Sébaco | 4:0 | ||||
| 13. Jornada | 21.10.2021 | Managua FC | - | H&H Export Sébaco | 1:2 | ||||
| 15. Jornada | 31.10.2021 | CD Walter Ferretti | - | H&H Export Sébaco | 2:1 |  |
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| 16. Jornada | 04.11.2021 | H&H Export Sébaco | - | ART Municipal Jalapa | 3:0 | ||||
| 18. Jornada | 20.11.2021 | H&H Export Sébaco | - | Real Madriz | 2:3 |
Nicaragua