| 1. Jornada | 16.01.2022 | Luis Ángel Firpo | - | Municipal Limeño | 1:0 | ||||
| 2. Jornada | 23.01.2022 | Municipal Limeño | - | Platense Zacatecoluca | 2:1 |  |
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| 3. Jornada | 26.01.2022 | Once Municipal | - | Municipal Limeño | 3:2 | |
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| 4. Jornada | 30.01.2022 | Municipal Limeño | - | CD Águila | 0:3 | |
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| 5. Jornada | 04.02.2022 | Jocoro FC | - | Municipal Limeño | 3:0 | ||||
| 9. Jornada | 23.02.2022 | Municipal Limeño | - | Atlético Marte | 2:0 | |
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| 10. Jornada | 27.02.2022 | Isidro Metapán | - | Municipal Limeño | 2:0 | ||||
| 11. Jornada | 06.03.2022 | Municipal Limeño | - | AD Chalatenango | 0:1 | ||||
| 17. Jornada | 13.04.2022 | FAS | - | Municipal Limeño | 1:1 | |
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| 19. Jornada | 24.04.2022 | Alianza | - | Municipal Limeño | 4:0 | |
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| 20. Jornada | 27.04.2022 | Atlético Marte | - | Municipal Limeño | 0:1 | ||||
| 21. Jornada | 01.05.2022 | Municipal Limeño | - | Isidro Metapán | 1:0 | |
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| 22. Jornada | 07.05.2022 | AD Chalatenango | - | Municipal Limeño | 0:0 |
El Salvador