| 19. Jornada | 13.02.2022 | FK Skopje | - | FK Borec | 1:1 | ||||
| 20. Jornada | 19.02.2022 | FK Borec | - | KF Shkëndija 79 | 0:3 | ||||
| 21. Jornada | 27.02.2022 | FK Borec | - | FC Struga | 0:1 | ||||
| 22. Jornada | 09.03.2022 | FK AP Brera Strumica | - | FK Borec | 5:0 | ||||
| 23. Jornada | 13.03.2022 | FK Bregalnica Štip | - | FK Borec | 3:0 | ||||
| 30. Jornada | 01.05.2022 | FK Borec | - | FK Skopje | 1:0 | ||||
| 31. Jornada | 04.05.2022 | FK Rabotnički | - | FK Borec | 2:1 | ||||
| 32. Jornada | 08.05.2022 | FK Pelister | - | FK Borec | 2:1 | ||||
| 33. Jornada | 15.05.2022 | FK Borec | - | FK Renova | 1:5 |
Macedonia del Norte