| 1. Jornada | 07.08.2022 | FK AP Brera Strumica | - | FK Bregalnica Štip | 1:2 | ||||
| 2. Jornada | 14.08.2022 | FK Rabotnički | - | FK AP Brera Strumica | 0:5 | ||||
| 3. Jornada | 21.08.2022 | FK AP Brera Strumica | - | KF Shkëndija 79 | 0:1 | ||||
| 4. Jornada | 27.08.2022 | Sileks Kratovo | - | FK AP Brera Strumica | 1:1 | ||||
| 5. Jornada | 31.08.2022 | FK AP Brera Strumica | - | FK Skopje | 3:0 | ||||
| 6. Jornada | 04.09.2022 | FK AP Brera Strumica | - | FC Struga | 0:3 | ||||
| 7. Jornada | 11.09.2022 | GFK Tikvesh | - | FK AP Brera Strumica | 2:1 |  |
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| 8. Jornada | 17.09.2022 | FK AP Brera Strumica | - | Makedonija GP | 0:1 | ||||
| 10. Jornada | 09.10.2022 | FK AP Brera Strumica | - | KF Shkupi | 0:1 | ||||
| 12. Jornada | 25.10.2022 | FK Bregalnica Štip | - | FK AP Brera Strumica | 1:0 | ||||
| 13. Jornada | 30.10.2022 | FK AP Brera Strumica | - | FK Rabotnički | 0:2 | ||||
| 14. Jornada | 06.11.2022 | KF Shkëndija 79 | - | FK AP Brera Strumica | 1:1 | ||||
| 16. Jornada | 27.11.2022 | FK Skopje | - | FK AP Brera Strumica | 2:1 |
Macedonia del Norte