| 15. Jornada | 30.10.2021 | Mazatlán FC [Sub 16] | - | Atlas Guadalajara [Sub 16] | 1:3 | ||||
| 16. Jornada | 06.11.2021 | Deportivo Guadalajara [Sub 16] | - | Atlas Guadalajara [Sub 16] | 3:0 | ||||
| 17. Jornada | 13.11.2021 | Atlas Guadalajara [Sub 16] | - | UANL Tigres [Sub 16] | 1:2 | ||||
| 18. Jornada | 20.11.2021 | Atlético San Luis [Sub 16] | - | Atlas Guadalajara [Sub 16] | 2:1 |  |
México