| 11. Jornada | 24.10.2020 | FC Nitra | - | MFK Zemplín Michalovce | 1:1 | ||||
| 12. Jornada | 31.10.2020 | Spartak Trnava | - | MFK Zemplín Michalovce | 1:2 | ||||
| 13. Jornada | 07.11.2020 | MFK Zemplín Michalovce | - | Slovan Bratislava | 0:2 | ||||
| 14. Jornada | 21.11.2020 | MFK Zemplín Michalovce | - | FK Senica | 0:1 | ||||
| 15. Jornada | 28.11.2020 | Zlaté Moravce | - | MFK Zemplín Michalovce | 0:0 | ||||
| 16. Jornada | 05.12.2020 | MFK Zemplín Michalovce | - | MŠK Žilina | 1:1 | ||||
| 17. Jornada | 13.12.2020 | AS Trenčín | - | MFK Zemplín Michalovce | 2:2 | ||||
| 18. Jornada | 16.12.2020 | MFK Zemplín Michalovce | - | MFK Ružomberok | 4:3 | ||||
| 19. Jornada | 14.02.2021 | FK Pohronie | - | MFK Zemplín Michalovce | 1:1 |  |
Eslovaquia