| 1. Jornada | 08.08.2020 | MFK Zemplín Michalovce | - | Spartak Trnava | 0:2 | ||||
| 2. Jornada | 11.08.2020 | Slovan Bratislava | - | MFK Zemplín Michalovce | 5:0 | ||||
| 3. Jornada | 15.08.2020 | FK Senica | - | MFK Zemplín Michalovce | 3:0 |  |
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| 4. Jornada | 25.08.2020 | MFK Zemplín Michalovce | - | Zlaté Moravce | 1:0 | ||||
| 5. Jornada | 30.08.2020 | MŠK Žilina | - | MFK Zemplín Michalovce | 6:2 | ||||
| 6. Jornada | 12.09.2020 | MFK Zemplín Michalovce | - | AS Trenčín | 1:1 | ||||
| 7. Jornada | 19.09.2020 | MFK Ružomberok | - | MFK Zemplín Michalovce | 4:0 | ||||
| 8. Jornada | 26.09.2020 | MFK Zemplín Michalovce | - | FK Pohronie | 2:0 | ||||
| 9. Jornada | 03.10.2020 | ŠKF Sereď | - | MFK Zemplín Michalovce | 1:1 | ||||
| 10. Jornada | 17.10.2020 | MFK Zemplín Michalovce | - | FC DAC 1904 | 2:4 | ||||
| 11. Jornada | 24.10.2020 | FC Nitra | - | MFK Zemplín Michalovce | 1:1 | ||||
| 16. Jornada | 05.12.2020 | MFK Zemplín Michalovce | - | MŠK Žilina | 1:1 | ||||
| 17. Jornada | 13.12.2020 | AS Trenčín | - | MFK Zemplín Michalovce | 2:2 | ||||
| 18. Jornada | 16.12.2020 | MFK Zemplín Michalovce | - | MFK Ružomberok | 4:3 | |
Eslovaquia