| 5. Jornada | 22.08.2021 | SV Zulte Waregem | - | Sporting Charleroi | 2:2 | ||||
| 6. Jornada | 28.08.2021 | Sporting Charleroi | - | K Beerschot VA | 5:2 |  |
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| 7. Jornada | 12.09.2021 | Gante | - | Sporting Charleroi | 2:3 | ||||
| 13. Jornada | 30.10.2021 | Sporting Charleroi | - | KAS Eupen | 3:0 | ||||
| 14. Jornada | 06.11.2021 | Union Saint-Gilloise | - | Sporting Charleroi | 4:0 | ||||
| 21. Jornada | 27.12.2021 | Sporting Charleroi | - | Oud-Heverlee Leuven | 0:3 | ||||
| 29. Jornada | 25.02.2022 | K Beerschot VA | - | Sporting Charleroi | 2:3 | ||||
| 31. Jornada | 12.03.2022 | KV Mechelen | - | Sporting Charleroi | 2:2 | ||||
| 32. Jornada | 19.03.2022 | Sporting Charleroi | - | Cercle Brugge | 5:0 | |
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| 33. Jornada | 03.04.2022 | RSC Anderlecht | - | Sporting Charleroi | 4:0 | ||||
| 34. Jornada | 10.04.2022 | Sporting Charleroi | - | SV Zulte Waregem | 3:0 |
Bélgica