| 4. Jornada | 30.01.2022 | Municipal Limeño | - | CD Águila | 0:3 | ||||
| 8. Jornada | 20.02.2022 | Municipal Limeño | - | Alianza | 0:0 | ||||
| 9. Jornada | 23.02.2022 | Municipal Limeño | - | Atlético Marte | 2:0 | ||||
| 10. Jornada | 27.02.2022 | Isidro Metapán | - | Municipal Limeño | 2:0 | ||||
| 12. Jornada | 13.03.2022 | Municipal Limeño | - | Luis Ángel Firpo | 3:2 | ||||
| 13. Jornada | 20.03.2022 | Platense Zacatecoluca | - | Municipal Limeño | 1:0 | ||||
| 15. Jornada | 03.04.2022 | CD Águila | - | Municipal Limeño | 1:0 | ||||
| 16. Jornada | 10.04.2022 | Municipal Limeño | - | Jocoro FC | 2:2 | ||||
| 17. Jornada | 13.04.2022 | FAS | - | Municipal Limeño | 1:1 |
El Salvador