| 1. Jornada | 06.02.2022 | Albion | - | Rentistas | 3:5 | ||||
| 3. Jornada | 20.02.2022 | Albion | - | Peñarol | 1:1 |  |
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| 4. Jornada | 28.02.2022 | Montevideo City Torque | - | Albion | 1:2 |  |
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| 5. Jornada | 13.03.2022 | Albion | - | Montevideo Wanderers | 1:1 | ||||
| 6. Jornada | 20.03.2022 | Plaza Colonia | - | Albion | 1:1 | ||||
| 7. Jornada | 02.04.2022 | Albion | - | Boston River | 1:2 | |
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| 8. Jornada | 10.04.2022 | River Plate | - | Albion | 4:1 | |
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| 9. Jornada | 16.04.2022 | Albion | - | Cerro Largo | 2:1 | ||||
| 10. Jornada | 24.04.2022 | Fénix | - | Albion | 2:1 | |
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| 11. Jornada | 07.05.2022 | Albion | - | Defensor Sporting | 0:3 | ||||
| 12. Jornada | 15.05.2022 | Albion | - | Cerrito | 2:2 | ||||
| 13. Jornada | 21.05.2022 | Nacional | - | Albion | 2:0 | ||||
| 14. Jornada | 27.05.2022 | Albion | - | Danubio | 1:2 | ||||
| 15. Jornada | 04.06.2022 | Deportivo Maldonado | - | Albion | 0:0 | |
Uruguay