| 3. Jornada | 27.01.2022 | Alianza | - | AD Chalatenango | 3:1 | ||||
| 4. Jornada | 30.01.2022 | AD Chalatenango | - | Luis Ángel Firpo | 2:1 |  |
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| 5. Jornada | 06.02.2022 | Platense Zacatecoluca | - | AD Chalatenango | 1:1 | |
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| 6. Jornada | 10.02.2022 | AD Chalatenango | - | Once Municipal | 1:0 | ||||
| 7. Jornada | 13.02.2022 | CD Águila | - | AD Chalatenango | 0:1 | ||||
| 8. Jornada | 20.02.2022 | AD Chalatenango | - | Jocoro FC | 1:0 | ||||
| 11. Jornada | 06.03.2022 | Municipal Limeño | - | AD Chalatenango | 0:1 | ||||
| 12. Jornada | 12.03.2022 | Atlético Marte | - | AD Chalatenango | 4:2 | ||||
| 14. Jornada | 25.03.2022 | AD Chalatenango | - | Alianza | 2:0 | ||||
| 15. Jornada | 03.04.2022 | Luis Ángel Firpo | - | AD Chalatenango | 1:2 | |
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| 16. Jornada | 10.04.2022 | AD Chalatenango | - | Platense Zacatecoluca | 1:2 | ||||
| 17. Jornada | 13.04.2022 | Once Municipal | - | AD Chalatenango | 0:1 | |
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| 18. Jornada | 17.04.2022 | AD Chalatenango | - | CD Águila | 0:0 | ||||
| 22. Jornada | 07.05.2022 | AD Chalatenango | - | Municipal Limeño | 0:0 |
El Salvador