| 3. Jornada | 03.09.2022 | Żebbuġ Rangers | - | St. Luċija FC | 2:0 |  |
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| 4. Jornada | 11.09.2022 | St. Luċija FC | - | Birkirkara FC | 0:4 | ||||
| 5. Jornada | 01.10.2022 | St. Luċija FC | - | Gudja United | 1:3 | ||||
| 6. Jornada | 08.10.2022 | Marsaxlokk FC | - | St. Luċija FC | 2:2 | ||||
| 7. Jornada | 16.10.2022 | St. Luċija FC | - | Hibernians FC | 2:3 | ||||
| 8. Jornada | 22.10.2022 | Pietá Hotspurs | - | St. Luċija FC | 1:2 | ||||
| 10. Jornada | 05.11.2022 | Floriana FC | - | St. Luċija FC | 1:0 | ||||
| 11. Jornada | 12.11.2022 | St. Luċija FC | - | Valletta FC | 0:2 | |
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| 12. Jornada | 04.12.2022 | Hamrun Spartans | - | St. Luċija FC | 2:0 | |
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| 13. Jornada | 11.12.2022 | St. Luċija FC | - | Mosta FC | 1:2 |
Malta