| 1. Jornada | 10.07.2022 | Managua FC | - | Club Deportivo Ocotal | 3:1 | ||||
| 2. Jornada | 17.07.2022 | Juventus Managua | - | Managua FC | 2:1 | ||||
| 3. Jornada | 25.07.2022 | Managua FC | - | CD Walter Ferretti | 1:2 |  |
|||
| 5. Jornada | 07.08.2022 | Diriangén FC | - | Managua FC | 0:0 | ||||
| 6. Jornada | 12.08.2022 | Managua FC | - | Real Estelí FC | 3:0 | ||||
| 7. Jornada | 14.08.2022 | H&H Export Sébaco | - | Managua FC | 2:1 | ||||
| 8. Jornada | 21.08.2022 | Matagalpa FC | - | Managua FC | 1:0 | ||||
| 4. Jornada | 25.08.2022 | Managua FC | - | ART Municipal Jalapa | 1:1 |  |
|||
| 12. Jornada | 02.10.2022 | CD Walter Ferretti | - | Managua FC | 2:1 | ||||
| 13. Jornada | 23.10.2022 | ART Municipal Jalapa | - | Managua FC | 0:3 | ||||
| 16. Jornada | 24.11.2022 | Managua FC | - | H&H Export Sébaco | 0:1 | ||||
| 18. Jornada | 01.12.2022 | UNAN Managua | - | Managua FC | 1:3 |
Nicaragua