| 1. Jornada | 16.01.2022 | AD Chalatenango | - | Atlético Marte | 0:0 | ||||
| 4. Jornada | 30.01.2022 | AD Chalatenango | - | Luis Ángel Firpo | 2:1 | ||||
| 5. Jornada | 06.02.2022 | Platense Zacatecoluca | - | AD Chalatenango | 1:1 | ||||
| 7. Jornada | 13.02.2022 | CD Águila | - | AD Chalatenango | 0:1 | ||||
| 8. Jornada | 20.02.2022 | AD Chalatenango | - | Jocoro FC | 1:0 |  |
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| 9. Jornada | 23.02.2022 | FAS | - | AD Chalatenango | 1:3 | ||||
| 10. Jornada | 27.02.2022 | AD Chalatenango | - | Santa Tecla FC | 1:0 | |
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| 11. Jornada | 06.03.2022 | Municipal Limeño | - | AD Chalatenango | 0:1 | ||||
| 12. Jornada | 12.03.2022 | Atlético Marte | - | AD Chalatenango | 4:2 | ||||
| 15. Jornada | 03.04.2022 | Luis Ángel Firpo | - | AD Chalatenango | 1:2 |  |
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| 17. Jornada | 13.04.2022 | Once Municipal | - | AD Chalatenango | 0:1 |  |
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| 20. Jornada | 28.04.2022 | AD Chalatenango | - | FAS | 3:2 | |
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| 21. Jornada | 02.05.2022 | Santa Tecla FC | - | AD Chalatenango | 1:0 | ||||
| 22. Jornada | 07.05.2022 | AD Chalatenango | - | Municipal Limeño | 0:0 |
El Salvador