| 2. Jornada | 31.10.2021 | Tala'ea El Gaish SC | - | Zamalek | 0:2 | ||||
| 4. Jornada | 19.11.2021 | Tala'ea El Gaish SC | - | Ghazl Al Mehalla | 0:0 | ||||
| 6. Jornada | 26.11.2021 | Tala'ea El Gaish SC | - | Future FC | 1:0 |  |
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| 7. Jornada | 21.12.2021 | Pyramids FC | - | Tala'ea El Gaish SC | 3:0 | ||||
| 8. Jornada | 09.02.2022 | Tala'ea El Gaish SC | - | El Gouna | 0:1 | ||||
| 9. Jornada | 14.02.2022 | Misr lel-Maqasah SC | - | Tala'ea El Gaish SC | 0:0 | ||||
| 10. Jornada | 21.02.2022 | Tala'ea El Gaish SC | - | Pharco FC | 1:0 |  |
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| 12. Jornada | 09.03.2022 | Tala'ea El Gaish SC | - | Al Masry Club | 1:0 | ||||
| 13. Jornada | 17.03.2022 | El Sharkia Lel Dokhan | - | Tala'ea El Gaish SC | 0:0 | ||||
| 14. Jornada | 14.04.2022 | Tala'ea El Gaish SC | - | ENPPI | 1:1 | ||||
| 15. Jornada | 19.04.2022 | Tala'ea El Gaish SC | - | Ceramica Cleopatra | 1:0 | ||||
| 18. Jornada | 09.05.2022 | Tala'ea El Gaish SC | - | National Bank SC | 1:1 | ||||
| 20. Jornada | 21.05.2022 | Tala'ea El Gaish SC | - | Al Mokawloon | 1:0 |
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