| 2. Jornada | 17.08.2019 | Southampton | - | Liverpool | 1:2 |  |
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| 3. Jornada | 24.08.2019 | Brighton & Hove Albion | - | Southampton | 0:2 |  |
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| 5. Jornada | 14.09.2019 | Sheffield United | - | Southampton | 0:1 | |
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| 11. Jornada | 02.11.2019 | Manchester City | - | Southampton | 2:1 | ||||
| 12. Jornada | 09.11.2019 | Southampton | - | Everton | 1:2 | ||||
| 13. Jornada | 23.11.2019 | Arsenal | - | Southampton | 2:2 | ||||
| 14. Jornada | 30.11.2019 | Southampton | - | Watford FC | 2:1 | ||||
| 15. Jornada | 04.12.2019 | Southampton | - | Norwich City | 2:1 | |
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| 16. Jornada | 08.12.2019 | Newcastle United | - | Southampton | 2:1 | ||||
| 17. Jornada | 14.12.2019 | Southampton | - | West Ham United | 0:1 | ||||
| 20. Jornada | 28.12.2019 | Southampton | - | Crystal Palace | 1:1 | ||||
| 21. Jornada | 01.01.2020 | Southampton | - | Tottenham Hotspur | 1:0 | |
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| 22. Jornada | 11.01.2020 | Leicester City | - | Southampton | 1:2 | ||||
| 23. Jornada | 18.01.2020 | Southampton | - | Wolverhampton Wanderers | 2:3 | ||||
| 25. Jornada | 01.02.2020 | Liverpool | - | Southampton | 4:0 | ||||
| 26. Jornada | 15.02.2020 | Southampton | - | Burnley FC | 1:2 | ||||
| 27. Jornada | 22.02.2020 | Southampton | - | Aston Villa | 2:0 | ||||
| 29. Jornada | 07.03.2020 | Southampton | - | Newcastle United | 0:1 |  |
Malí