| 1. Jornada | 03.02.2019 | Real Cartagena | - | Orsomarso SC | 1:1 | ||||
| 2. Jornada | 09.02.2019 | Valledupar FC | - | Real Cartagena | 1:1 | ||||
| 3. Jornada | 17.02.2019 | Real Cartagena | - | Tigres FC | 2:0 |  |
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| 4. Jornada | 21.02.2019 | Atlético FC | - | Real Cartagena | 0:3 | ||||
| 5. Jornada | 24.02.2019 | Real Cartagena | - | Deportes Quindío | 2:1 | ||||
| 6. Jornada | 28.02.2019 | Barranquilla FC | - | Real Cartagena | 2:1 |  |
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| 7. Jornada | 09.03.2019 | Real Cartagena | - | Fortaleza FC | 2:0 | ||||
| 8. Jornada | 17.03.2019 | Llaneros FC | - | Real Cartagena | 0:2 | ||||
| 9. Jornada | 25.03.2019 | Real Cartagena | - | Boyacá Chicó | 2:1 | |
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| 10. Jornada | 31.03.2019 | Bogotá FC | - | Real Cartagena | 1:0 | ||||
| 11. Jornada | 07.04.2019 | Real Cartagena | - | Cortuluá | 3:2 | |
Panamá