| 1. Jornada | 19.03.2022 | OFI Heraklion | - | Ionikos Nikea | 2:3 | ||||
| 2. Jornada | 02.04.2022 | Lamia | - | OFI Heraklion | 1:2 |  |
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| 3. Jornada | 09.04.2022 | OFI Heraklion | - | Apollon Smyrnis | 1:2 | ||||
| 4. Jornada | 17.04.2022 | Atromitos | - | OFI Heraklion | 1:1 | ||||
| 5. Jornada | 30.04.2022 | OFI Heraklion | - | Panetolikos | 0:1 | |
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| 6. Jornada | 08.05.2022 | OFI Heraklion | - | Asteras Tripolis | 1:0 |
Grecia