| 2. Jornada | 31.07.2021 | Mazatlán FC [Sub 16] | - | Atlético San Luis [Sub 16] | 4:0 | ||||
| 12. Jornada | 09.10.2021 | Mazatlán FC [Sub 16] | - | Santos Laguna [Sub 16] | 1:2 | ||||
| 13. Jornada | 16.10.2021 | Club León [Sub 16] | - | Mazatlán FC [Sub 16] | 4:1 | ||||
| 15. Jornada | 30.10.2021 | Mazatlán FC [Sub 16] | - | Atlas Guadalajara [Sub 16] | 1:3 | ||||
| 17. Jornada | 13.11.2021 | Mazatlán FC [Sub 16] | - | Club Necaxa [Sub 16] | 2:1 |
México