| 2. Jornada | 07.08.2022 | Vida | - | Olancho FC | 1:0 | ||||
| 3. Jornada | 11.08.2022 | Honduras Progreso | - | Olancho FC | 2:2 | ||||
| 4. Jornada | 14.08.2022 | Olancho FC | - | Olimpia | 0:1 | ||||
| 5. Jornada | 21.08.2022 | Real Sociedad | - | Olancho FC | 1:2 |  |
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| 6. Jornada | 28.08.2022 | Olancho FC | - | Motagua | 0:1 | ||||
| 7. Jornada | 01.09.2022 | Lobos UPNFM | - | Olancho FC | 1:2 | |
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| 8. Jornada | 04.09.2022 | Olancho FC | - | Real España | 3:1 | ||||
| 9. Jornada | 11.09.2022 | Olancho FC | - | Marathón | 2:3 | ||||
| 10. Jornada | 18.09.2022 | Victoria | - | Olancho FC | 2:1 | |
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| 12. Jornada | 09.10.2022 | Olancho FC | - | Honduras Progreso | 2:1 | ||||
| 13. Jornada | 17.10.2022 | Olimpia | - | Olancho FC | 0:1 | ||||
| 14. Jornada | 20.10.2022 | Olancho FC | - | Real Sociedad | 7:0 | ||||
| 15. Jornada | 24.10.2022 | Motagua | - | Olancho FC | 1:3 | ||||
| 16. Jornada | 06.11.2022 | Olancho FC | - | Lobos UPNFM | 3:0 | ||||
| 17. Jornada | 13.11.2022 | Real España | - | Olancho FC | 4:3 | |
Honduras