| 1. Jornada | 19.09.2021 | Lobos ULMX | - | Sporting Canamy | 0:0 | ||||
| 2. Jornada | 26.09.2021 | Sporting Canamy | - | Reboceros de La Piedad | 0:3 |  |
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| 3. Jornada | 02.10.2021 | Deportivo Dongu | - | Sporting Canamy | 1:2 | ||||
| 4. Jornada | 10.10.2021 | Sporting Canamy | - | Cañoneros FC | 0:2 | |
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| 6. Jornada | 17.10.2021 | Sporting Canamy | - | Escorpiones | 2:1 | ||||
| 7. Jornada | 25.10.2021 | Cafetaleros de Chiapas | - | Sporting Canamy | 1:1 | ||||
| 8. Jornada | 31.10.2021 | Sporting Canamy | - | CD Zap | 0:1 | |
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| 9. Jornada | 06.11.2021 | Inter de Querétaro | - | Sporting Canamy | 1:0 | ||||
| 10. Jornada | 10.11.2021 | Sporting Canamy | - | Montañeses FC | 2:1 | ||||
| 11. Jornada | 13.11.2021 | Leviatán FC | - | Sporting Canamy | 0:3 | ||||
| 12. Jornada | 19.11.2021 | Inter Playa | - | Sporting Canamy | 7:1 | |
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| 13. Jornada | 27.11.2021 | Sporting Canamy | - | Yalmakan FC | 0:3 |
México