| 6. Jornada | 31.07.2022 | Club León [Sub 18] | - | CF América [Sub 18] | 2:1 | ||||
| 8. Jornada | 13.08.2022 | Pumas UNAM [Sub 18] | - | CF América [Sub 18] | 1:2 | ||||
| 10. Jornada | 20.08.2022 | CF América [Sub 18] | - | Cruz Azul [Sub 18] | 2:0 | ||||
| 16. Jornada | 23.08.2022 | Gallos Blancos [Sub 18] | - | CF América [Sub 18] | 0:1 | ||||
| 12. Jornada | 03.09.2022 | CF América [Sub 18] | - | UANL Tigres [Sub 18] | 2:1 | ||||
| 13. Jornada | 06.09.2022 | CF América [Sub 18] | - | Atlético San Luis [Sub 18] | 4:1 | ||||
| 14. Jornada | 10.09.2022 | Club Necaxa [Sub 18] | - | CF América [Sub 18] | 0:4 | ||||
| 5. Jornada | 14.09.2022 | CF América [Sub 18] | - | Santos Laguna [Sub 18] | 5:1 | ||||
| 15. Jornada | 17.09.2022 | CF América [Sub 18] | - | Deportivo Guadalajara [Sub 18] | 0:3 |
México