| 4. Jornada | 11.08.2018 | FK Senica | - | FK Železiarne Podbrezová | 1:1 | ||||
| 5. Jornada | 18.08.2018 | MFK Zemplín Michalovce | - | FK Senica | 1:1 | ||||
| 6. Jornada | 25.08.2018 | FK Senica | - | FC Nitra | 1:1 | ||||
| 7. Jornada | 01.09.2018 | MFK Ružomberok | - | FK Senica | 4:0 | ||||
| 8. Jornada | 15.09.2018 | FK Senica | - | AS Trenčín | 0:2 | ||||
| 9. Jornada | 22.09.2018 | MŠK Žilina | - | FK Senica | 5:0 | ||||
| 10. Jornada | 29.09.2018 | FK Senica | - | FC DAC 1904 | 1:2 | ||||
| 11. Jornada | 06.10.2018 | Slovan Bratislava | - | FK Senica | 2:2 |  |
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| 12. Jornada | 20.10.2018 | Spartak Trnava | - | FK Senica | 4:1 | ||||
| 13. Jornada | 27.10.2018 | FK Senica | - | ŠKF Sereď | 0:0 |  |
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| 15. Jornada | 10.11.2018 | FK Železiarne Podbrezová | - | FK Senica | 2:4 | ||||
| 16. Jornada | 24.11.2018 | FK Senica | - | MFK Zemplín Michalovce | 2:4 | ||||
| 19. Jornada | 16.02.2019 | AS Trenčín | - | FK Senica | 3:0 | ||||
| 22. Jornada | 09.03.2019 | FK Senica | - | Slovan Bratislava | 1:2 | |
Ghana