| 22. Jornada | 16.01.2022 | RSC Anderlecht | - | Standard Liège | 1:1 |  |
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| 23. Jornada | 23.01.2022 | Standard Liège | - | Club Brugge KV | 2:2 |  |
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| 24. Jornada | 26.01.2022 | KAS Eupen | - | Standard Liège | 0:2 | |
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| 25. Jornada | 30.01.2022 | Standard Liège | - | KV Mechelen | 1:2 | ||||
| 26. Jornada | 05.02.2022 | Standard Liège | - | Cercle Brugge | 1:1 | ||||
| 27. Jornada | 13.02.2022 | KRC Genk | - | Standard Liège | 2:0 | |
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| 28. Jornada | 19.02.2022 | KV Oostende | - | Standard Liège | 1:0 | |
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| 31. Jornada | 13.03.2022 | Standard Liège | - | RFC Seraing | 0:1 | ||||
| 32. Jornada | 20.03.2022 | KV Kortrijk | - | Standard Liège | 0:1 | ||||
| 33. Jornada | 03.04.2022 | Standard Liège | - | Union Saint-Gilloise | 1:3 | ||||
| 34. Jornada | 10.04.2022 | Sint-Truidense VV | - | Standard Liège | 3:0 | |
Bélgica