| 1. Jornada | 01.09.2016 | Montevideo Wanderers | - | River Plate | 1:1 | ||||
| 2. Jornada | 04.09.2016 | River Plate | - | Boston River | 1:5 | ||||
| 3. Jornada | 11.09.2016 | Juventud de Las Piedras | - | River Plate | 0:0 | ||||
| 4. Jornada | 18.09.2016 | River Plate | - | Defensor Sporting | 0:5 | ||||
| 5. Jornada | 25.09.2016 | River Plate | - | Sud América | 0:3 | ||||
| 6. Jornada | 01.10.2016 | River Plate | - | Fénix | 1:2 | ||||
| 8. Jornada | 16.10.2016 | River Plate | - | Plaza Colonia | 2:1 | ||||
| 14. Jornada | 03.12.2016 | River Plate | - | Peñarol | 3:1 |  |
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| 15. Jornada | 10.12.2016 | CA Cerro | - | River Plate | 0:1 |  |
Brasil